InforLorV4, Main, Exploration, bibRecord, 000155

Classification and Exploration of 3D Protein Domain Interactions Using Kbdock.

Identifieur interne : 000155 ( Main/Exploration ); précédent : 000154; suivant : 000156

Classification and Exploration of 3D Protein Domain Interactions Using Kbdock.

Auteurs : Anisah W. Ghoorah ; Marie-Dominique Devignes [France] ; Malika Smaïl-Tabbone [France] ; David W. Ritchie [France]

Source :

Methods in molecular biology (Clifton, N.J.) [ 1940-6029 ] ; 2016.

RBID : pubmed:27115629

Abstract

Comparing and classifying protein domain interactions according to their three-dimensional (3D) structures can help to understand protein structure-function and evolutionary relationships. Additionally, structural knowledge of existing domain-domain interactions can provide a useful way to find structural templates with which to model the 3D structures of unsolved protein complexes. Here we present a straightforward guide to using the "Kbdock" protein domain structure database and its associated web site for exploring and comparing protein domain-domain interactions (DDIs) and domain-peptide interactions (DPIs) at the Pfam domain family level. We also briefly explain how the Kbdock web site works, and we provide some notes and suggestions which should help to avoid some common pitfalls when working with 3D protein domain structures.

DOI: 10.1007/978-1-4939-3572-7_5
PubMed: 27115629

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Comparing and classifying protein domain interactions according to their three-dimensional (3D) structures can help to understand protein structure-function and evolutionary relationships. Additionally, structural knowledge of existing domain-domain interactions can provide a useful way to find structural templates with which to model the 3D structures of unsolved protein complexes. Here we present a straightforward guide to using the "Kbdock" protein domain structure database and its associated web site for exploring and comparing protein domain-domain interactions (DDIs) and domain-peptide interactions (DPIs) at the Pfam domain family level. We also briefly explain how the Kbdock web site works, and we provide some notes and suggestions which should help to avoid some common pitfalls when working with 3D protein domain structures.</div>
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Classification and Exploration of 3D Protein Domain Interactions Using Kbdock.

Classification and Exploration of 3D Protein Domain Interactions Using Kbdock.

Source :

Abstract

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